The Central Intelligence training program Treadstone produced two graduates of equal skill and determination--Jason Bourne and a vicious Russian mercenary, Leonid Arkadin. As Bourne's destiny circles closer to Arkadin's, it becomes clear that the eventual collision of these men is not of their own making. Someone else has been watching and manipulating them. Someone who wants to know, "Who is the more deadly agent?"

Jason Bourne has reassumed his identity as David Webb, becoming a university linguistics teacher and spending time with his family. However, after being framed for the murder of his two closest friends, Bourne is on the run again. Now, Bourne must go toe-to-toe with an assassin who is closely linked to his past.