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1) Cancer World
Author
Publisher
Feedbooks
Pub. Date
2023
Language
English
Description
Greg tried desperately to find an illegal method of joining his family on Mars; for the law said that no healthy man could land on a— CANCER WORLD
Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
Excerpt
1. Introduction
According to the GLOBOCAN 2008 estimates, about 12.7 million cancer cases and 7.6
million cancer deaths are estimated to have occurred in 2008; of these, 56% of the cases and
64% of the deaths occurred in the economically developing world (Jemal et al., 2011).
It is now 51 years since Macfarlane Burnet and Peter Medawar won the Nobel Prize in
Physiology or Medicine for the discovery of acquired immunological tolerance, and...
Author
Publisher
IntechOpen
Pub. Date
2024
Language
English
Description
Carcinogens are substances that induce cancer by damaging the genome or through disruption of cellular metabolic processes. Some compounds interact directly with DNA, while others are activated to reactive molecules that can bind with DNA by covalent adducts causing mutations in genes crucial to biological processes. Cigarette smoke is by far the most important and notorious carcinogen. Cigarette smoke contains many carcinogenic substances including...
Author
Publisher
ABDO Publishing Company
Pub. Date
2022
Language
English
Description
Living with Cancer features fictional narratives paired with firsthand advice from a medical expert to help preteens and teenagers feel prepared for dealing with cancer during adolescence. Topics include tests and diagnosis, cancer in teens, treatment, the effects of treatment, coping and getting support, relationships, dealing with school, and the future after treatment ends. Throughout the book, Ask Yourself This questions encourage discussion....
Author
Publisher
Books on Tape
Pub. Date
2023
Language
English
Description
Moving between journal entry, memoir, and exposition, Audre Lorde fuses the personal and political as she reflects on her experience coping with breast cancer and a radical mastectomy.
A Penguin Classic
First published over forty years ago, The Cancer Journals is a startling, powerful account of Audre Lorde's experience with breast cancer and mastectomy. Long before narratives explored the silences around illness and women's...
A Penguin Classic
First published over forty years ago, The Cancer Journals is a startling, powerful account of Audre Lorde's experience with breast cancer and mastectomy. Long before narratives explored the silences around illness and women's...
Publisher
Frontiers Media
Pub. Date
2024
Language
English
Description
Macroautophagy, the major lysosomal pathway for recycling intracellular components including whole organelles, has emerged as a key process modulating tumorigenesis, tumor-stroma interactions, and cancer therapy. An impressive number of studies over the past decade have unraveled the plastic role of autophagy during tumor development and dissemination. The discoveries that autophagy may either support or repress neoplastic growth and contextually
...Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
There has been increased concern surrounding exposure to heavy metals due to the evolving understanding of their role in the development of cancer. This review highlights research related to the impact that heavy metals aluminum, arsenic, beryllium, cadmium, lead, mercury, nickel and radium have on human health. Research was collected through PubMed, and it was compiled to assess the current knowledge of exposure sources, types of cancers induced...
Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
Excerpt
It has become an acknowledged fact that Colorectal Cancer (CRC) is a worldwide problem, with an annual incidence of approximately 1 million cases and an annual mortality of more than 500,000. Furthermore, the absolute number of cases will increase over the next two decades as a result of the aging and expansion of populations in both the developed and developing countries.
(Book chapter in Colorectal Cancer edited by Jim S. Khan)
Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
The relationship between breast cancer and scleroderma is complex, involving aspects of epidemiological coexistence, pathophysiology and treatment. Increased risk of malignancy is known to occur in scleroderma patients particularly lung and breast cancer. Risk factors for breast cancer in scleroderma patients include older age and autoimmunity status (lack of ANA positivity). The sometimes close temporal relationship between breast cancer and scleroderma...
Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
With the unavoidable progress of genomics technologies, “one size fits all” strategy has switched to individual-specific treatment approaches. Hence pharmacogenomics-based personalized cancer medicine has emerged. Promising treatment option immunotherapy includes either “take the brakes off immune system (i.e., checkpoint blockade therapy) or the use of immune cells expanded in an in vitro tumor-free environment’’. Both options have been...
Author
Publisher
Morressier
Pub. Date
2024
Language
English
Description
Treatment of Ovarian cancer is usually multimodal and carries significant morbidity. Plasmajet appears to reduce the morbidity and in particular reducing the requirement for bowel surger. The aim of this study was to evaluate the histological appearance of peritoneum infiltrated by ovarian or primary peritoneal cancer treated by plasmajet energy device at surgery. We found that in 75% of the cases the tumour can be destroyed successfully...
Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
Cancer Stem Cells and Chemoresistance
. Published data, so far, has not yet confirmed the benefit of these approaches in chemoresistant patients where CSCs are believed to be the predominant factor. If CSCs are key molecules responsible for chemoresistance, there is an urgent need to enhance both experimental and clinical studies
to support the use of these biological therapies in chemoresistant breast cancers. It is likely
that additional agents,...
Author
Publisher
IntechOpen
Pub. Date
2024
Language
English
Description
Excerpt
1. Introduction
The three mainstays for cancer treatment include surgical removal of tumors, radiation therapy and chemotherapy, which have led to improved patient survival for certain types of cancer, but there is still much room for improvement. Cancer is one of the leading causes of death worldwide and accounted for 7.6 million deaths (13% of all deaths) in 2008 (World Health Organization, 2012). The 2012 Report to the Nation on the Status...
Author
Publisher
IntechOpen
Pub. Date
2024
Language
English
Description
Excerpt
Targeted therapy in cancer has led to intensive searches for the molecular pathways of malignant transformation [1]. In gynecologic malignancies, BRCA 1 and BRCA 2 gene mutations on chromosomes 17 and 13 respectively were identified in the 1990s [2]. Since then, intensive investigation of the pathways for these genes has led to a wealth of information about molecular pathways [3]. The understanding of these molecular pathways has led in turn...
Author
Publisher
IntechOpen
Pub. Date
2023
Language
English
Description
Excerpt
1. Introduction
Pancreatic cancer is the fourth most frequent cause of cancer-related deaths; it also represents one of the most aggressive cancer types, with a high incidence of distant metastasis and mortality [1]. The detection of pancreatic cancer at early stages, the prediction of the potential resectability, or the response to therapy are the current major challenges in improving the clinical outcome of pancreatic ductal adenocarcinoma...
Publisher
Frontiers Media
Pub. Date
2023
Language
English
Description
Cancer care delivery refers to the multiple layers of the health care system that interact to affect outcomes for patients with cancer and the quality of that care. The factors included in the care delivery system that potentially alters outcomes include social dynamics, financing systems, organizational structures and processes, health technologies, and provider and individual behaviors. Because women’s health care has its own unique challenges,
...Publisher
Frontiers Media
Pub. Date
2024
Language
English
Description
For the faultless function of the immune system, tight regulation of immune cell activation, immuno-suppression, and the strength and efficiency of the immune response is essential. Immune checkpoint (ICP) molecules can amplify or dampen signals that lead to the modulation of specific immune activities. Under physiological conditions, immune checkpoints are essential to prevent autoimmune manifestations and to preserve self-tolerance. They help
...Publisher
Routledge
Pub. Date
2024
Language
English
Description
Cancer is a transnational condition involving the unprecedented flow of health information, technologies, and people across national borders. Such movement raises questions about the nature of therapeutic citizenship, how and where structurally vulnerable populations obtain care, and the political geography of blame associated with this disease. This volume brings together cutting-edge anthropological research carried out across North and South America,...
Author
Publisher
Morressier
Pub. Date
2023
Language
English
Description
Introduction: Brain metastasis (BM) from ovarian cancer is a rare disease leading to limited survival. Aim is to evaluate risk factors and survival for BM from epithelial ovarian cancer (EOC). Methodology:A total of 24 patients diagnosed with metachronous BM after therapy of primary ovarian cancer treated at university Tuebingen from 01/2000 to 3/2019, were retrospectively analyzed.Results:Age at first diagnosis was 56 years (range 42-71y) in median;...
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