The remaining Alchemist Warriors head for Papillon Masks hideout to put an end to everything. But is Papillon Mask really going to carry out his mission to burn the entire world to the ground?

Kazuki Muto was transformed into a Buso Renkin by Tokiko after he was killed by a homunculus, a flesh-eating monster. Now, Kazuki and Tokiko are racing against time to find the creator of the homunculi before the one that is lodged at Tokiko's waist reaches her brain and transforms her into a homunculus. Unknown to them, the person they seek is a student at Kazuki's school.

Upon arriving at the headquarters of the L.X.E., the Alchemist Warriors learn of the League's plot to attack the high schoo. They immediately head over there, only to discover that the school is surrounded by Dr. Butterfly's humunculus soldiers. Plus, they'll have to face the students, too!

The Shinsengumi--fearsome and formidable protectors of the Shogunate. Kenshin knows them well...

Kenshin and his comrades have finally discovered the location of Enishi's island compund, but to free Kaoru from captivity, a good deal of fighting will be necessary. Woo Heishin, Enishi's mysterious second-in-command, meets them on the beach and brings his deadly bodyguards, the Su-Shin or the "Four Stars," to serve as a welcoming committee. Yahiko, Sanosuke, Saito and Aoshi dive into combat with Woo Heishin's warriors as Kenshin prepares himself...