Growing up in Saitter, Louisiana, in the 1950s, twelve-year-old Tiger Ann struggles with her feelings about her stern, but loving grandmother, her mentally slow parents, and her good friend and neighbor, Jesse.

Katy, the precocious ten-year-old daughter of the town doctor, befriends a retarded boy.

After a fight at school leaves Marcus facing suspension, Marcus's mother takes him and his younger brother, who has Down syndrome, to Puerto Rico to visit relatives they do not remember or have never met, and while there Marcus starts searching for his father, who left their family ten years ago and is somewhere on the island.

Luther T. Farrel has got to get out of Flint, Michigan. As his best friend Sparky says, "Flint's nothing but the Titanic." And his mother, a.k.a. the Sarge, says, "Take my advice and stay off the sucker path." The Sarge milked the system to build an empire of slum housing and group homes. Luther's just one of the many people trapped in the Sarge's Evil Empire-but he's about to bust out. If Luther wins the science fair this year, he'll be on track...